A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury

Key Points

Question  Can a conservative dialysis strategy improve recovery of kidney function for patients with acute kidney injury who require dialysis?

Findings  In this randomized clinical trial with 220 adults, dialyzing based on specific metabolic or clinical indications increased the likelihood of achieving recovery of kidney function at hospital discharge (64%) compared with the conventional treatment of 3 times per week (50%).

Meaning  A conservative dialysis strategy promoted recovery from dialysis-requiring acute kidney injury.

Conclusions

This trial showed that for patients with AKI-D who are hemodynamically stable, a conservative dialysis strategy—performing dialysis only when specific metabolic or clinical indications are met—resulted in less health care resource use and better clinical outcomes, including sooner and more frequent liberation from dialysis

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